Oprah has been involved in many interviews from both sides of the spectrum, being the interviewer as well as being the one interviewed. Over the years there has been one thing for certain and that is Oprah has the power to make anyone cry.
Not even five minutes into being on the Tonight Show with James Corden had him tearing up. Even Reese Witherspoon admitted to crying in less that five minutes during her 2005 interview with Oprah.
It’s not something Oprah does purposely. I think at this point in Oprah‘s career when people get interviewed by her or just talk to her they get a sense of amazement which leads to them feeling overwhelmed. That’s my guess at least.